Epidemiology, pathophysiology, diagnosis and management of chronic right-sided heart failure and tricuspid regurgitation. A clinical consensus statement of the Heart Failure Association (HFA) and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC

Marianna Adamo, Ovidiu Chioncel, Matteo Pagnesi, Antoni Bayes-Genis, Magdy Abdelhamid, Stefan D. Anker, Elena Laura Antohi, Luigi Badano, Tuvia Ben Gal, Michael Böhm, Victoria Delgado, Julien Dreyfus, Francesco F. Faletra, Dimitrios Farmakis, Gerasimos Filippatos, Julia Grapsa, Finn Gustafsson, Jörg Hausleiter, Tiny Jaarsma, Nicole KaramLars Lund, Philipp Lurz, Francesco Maisano, Brenda Moura, Wilfred Mullens, Fabien Praz, Anna Sannino, Gianluigi Savarese, Carlo Gabriele Tocchetti, Vanessa P.M. van Empel, Ralph Stephan von Bardeleben, Mehmet Birhan Yilmaz, José Luis Zamorano, Piotr Ponikowski, Emanuele Barbato, Giuseppe M.C. Rosano, Marco Metra*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Right-sided heart failure and tricuspid regurgitation are common and strongly associated with poor quality of life and an increased risk of heart failure hospitalizations and death. While medical therapy for right-sided heart failure is limited, treatment options for tricuspid regurgitation include surgery and, based on recent developments, several transcatheter interventions. However, the patients who might benefit from tricuspid valve interventions are yet unknown, as is the ideal time for these treatments given the paucity of clinical evidence. In this context, it is crucial to elucidate aetiology and pathophysiological mechanisms leading to right-sided heart failure and tricuspid regurgitation in order to recognize when tricuspid regurgitation is a mere bystander and when it can cause or contribute to heart failure progression. Notably, early identification of right heart failure and tricuspid regurgitation may be crucial and optimal management requires knowledge about the different mechanisms and causes, clinical course and presentation, as well as possible treatment options. The aim of this clinical consensus statement is to summarize current knowledge about epidemiology, pathophysiology and treatment of tricuspid regurgitation in right-sided heart failure providing practical suggestions for patient identification and management.

Original languageEnglish
Pages (from-to)18-33
Number of pages16
JournalEuropean Journal of Heart Failure
Volume26
Issue number1
DOIs
StatePublished - Jan 2024

Keywords

  • Consensus statement
  • Right heart failure
  • Tricuspid regurgitation

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