TY - JOUR
T1 - Epidemiological aspects of travel-related systemic endemic mycoses
T2 - A GeoSentinel analysis, 1997-2017
AU - the GeoSentinel Surveillance Network
AU - Salzer, Helmut J.F.
AU - Stoney, Rhett J.
AU - Angelo, Kristina M.
AU - Rolling, Thierry
AU - Grobusch, Martin P.
AU - Libman, Michael
AU - López-Vélez, Rogelio
AU - Duvignaud, Alexandre
AU - Ásgeirsson, Hilmir
AU - Crespillo-Andújar, Clara
AU - Schwartz, Eli
AU - Gautret, Philippe
AU - Bottieau, Emmanuel
AU - Jordan, Sabine
AU - Lange, Christoph
AU - Hamer, Davidson H.
AU - Waggoner, Jesse
AU - Wu, Henry
AU - Plewes, Katherine
AU - Ghesquiere, Wayne
AU - Boggild, Andrea
AU - Kain, Kevin
AU - Goorhuis, Abraham
AU - Leung, Daniel
AU - Benson, Scott
AU - Kuhn, Susan
AU - Gkrania-Klotsas, Effrosyni
AU - Warne, Ben
AU - Lalloo, David
AU - Beeching, Nicholas
AU - Yansouni, Cedric
AU - von Sonnenburg, Frank
AU - Rothe, Camilla
AU - Lim, Poh Lian
AU - Schlagenhauf, Patricia
AU - Weber, Rainer
AU - Castelli, Francesco
AU - Matteelli, Alberto
AU - Leder, Karin
AU - Torresi, Joseph
AU - Clerinx, Johannes
AU - Coyle, Christina
AU - Kelly, Paul
AU - Vinnemeier, Christof
AU - Javelle, Emilie
AU - McCarthy, Anne
AU - Glans, Hedvig
N1 - Publisher Copyright:
© International Society of Travel Medicine, 2018. Published by Oxford University Press. All rights reserved.
PY - 2018
Y1 - 2018
N2 - Background: International travel has increased in the past few decades, placing more travellers at risk of acquiring systemic endemic mycoses. There are limited published data on systemic endemic mycoses among international travellers. We report epidemiological characteristics of non-migrant, international travellers who acquired systemic endemic mycoses during travel. Methods: We analysed records of non-migrant international travellers with a confirmed diagnosis of histoplasmosis, coccidioidomycosis, paracoccidioidomycosis, blastomycosis or talaromycosis reported from 1997 through 2017 to GeoSentinel, a global surveillance network now consisting of 70 travel or tropical medicine centres in 31 countries. Results: Sixty-nine records met the inclusion criteria. Histoplasmosis was most frequently reported; the 51 travellers with histoplasmosis had the lowest median age (30 years; range: 8-85) and shortest median duration of travel (12 days; range: 5-154). Coccidioidomycosis was reported in 14 travellers; travellers with coccidioidomycosis were older (median 62 years; range: 22-78) and had the longest median number of days between return from travel and presentation to a GeoSentinel site (55 days; range: 17-273). Almost all travellers with coccidioidomycosis were exposed in the USA. Other systemic endemic mycoses were less frequently reported, including blastomycosis (three travellers) and talaromycosis (one traveller). Conclusions: Although relatively rare, systemic endemic mycoses should be considered as potential travel-related infections in non-migrant international travellers. Epidemiological exposures should be used to guide diagnostic evaluations and treatment.
AB - Background: International travel has increased in the past few decades, placing more travellers at risk of acquiring systemic endemic mycoses. There are limited published data on systemic endemic mycoses among international travellers. We report epidemiological characteristics of non-migrant, international travellers who acquired systemic endemic mycoses during travel. Methods: We analysed records of non-migrant international travellers with a confirmed diagnosis of histoplasmosis, coccidioidomycosis, paracoccidioidomycosis, blastomycosis or talaromycosis reported from 1997 through 2017 to GeoSentinel, a global surveillance network now consisting of 70 travel or tropical medicine centres in 31 countries. Results: Sixty-nine records met the inclusion criteria. Histoplasmosis was most frequently reported; the 51 travellers with histoplasmosis had the lowest median age (30 years; range: 8-85) and shortest median duration of travel (12 days; range: 5-154). Coccidioidomycosis was reported in 14 travellers; travellers with coccidioidomycosis were older (median 62 years; range: 22-78) and had the longest median number of days between return from travel and presentation to a GeoSentinel site (55 days; range: 17-273). Almost all travellers with coccidioidomycosis were exposed in the USA. Other systemic endemic mycoses were less frequently reported, including blastomycosis (three travellers) and talaromycosis (one traveller). Conclusions: Although relatively rare, systemic endemic mycoses should be considered as potential travel-related infections in non-migrant international travellers. Epidemiological exposures should be used to guide diagnostic evaluations and treatment.
KW - GeoSentinel
KW - Systemic endemic mycoses
KW - Traveller
UR - http://www.scopus.com/inward/record.url?scp=85063712824&partnerID=8YFLogxK
U2 - 10.1093/jtm/tay055
DO - 10.1093/jtm/tay055
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C2 - 30085265
AN - SCOPUS:85063712824
SN - 1195-1982
VL - 25
JO - Journal of Travel Medicine
JF - Journal of Travel Medicine
IS - 1
M1 - tay055
ER -