Epidemiological and viral genomic sequence analysis of the 2014 Ebola outbreak reveals clustered transmission

Samuel V. Scarpino, Atila Iamarino, Chad Wells, Dan Yamin, Martial Ndeffo-Mbah, Natasha S. Wenzel, Spencer J. Fox, Tolbert Nyenswah, Frederick L. Altice, Alison P. Galvani, Lauren Ancel Meyers, Jeffrey P. Townsend*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Using Ebolavirus genomic and epidemiological data, we conducted the first joint analysis in which both data types were used to fit dynamic transmission models for an ongoing outbreak. Our results indicate that transmission is clustered, highlighting a potential bias in medical demand forecasts, and provide the first empirical estimate of underreporting.

Original languageEnglish
Pages (from-to)1079-1082
Number of pages4
JournalClinical Infectious Diseases
Volume60
Issue number7
DOIs
StatePublished - 1 Apr 2015
Externally publishedYes

Keywords

  • Ebola
  • West Africa
  • clustering
  • epidemiology
  • genome sequencing

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