Epicardial ablation of ventricular tachycardia: An institutional experience of safety and efficacy

Roderick Tung, Yoav Michowitz, Ricky Yu, Nilesh Mathuria, Marmar Vaseghi, Eric Buch, Jason Bradfield, Osamu Fujimura, Jean Gima, William Discepolo, Ravi Mandapati, Kalyanam Shivkumar*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

126 Scopus citations

Abstract

Background: Epicardial ablation has been shown to be a useful adjunct for treatment of ventricular tachycardia (VT). Objective: To report the trends, safety, and efficacy of epicardial mapping and ablation at a single center over an 8-year period. Methods: Patients referred for VT ablation (June 2004 to July 2011) were divided into 3 groups: ischemic cardiomyopathy (ICM), nonischemic cardiomyopathy (NICM), and idiopathic ventricular arrhythmias (VA). Patients with scar-mediated VT who underwent combined epicardial and endocardial (epi-endo) mapping and ablation were compared with those who underwent endocardial-only (endo-only) ablation with regard to patient characteristics, acute procedural success, 6- and 12-month clinical outcomes. Results: Among 144 patients referred for VT ablation, 95 patients underwent 109 epicardial procedures (94% access rate). Major complications were seen in 8 patients (8.8%) with pericardial bleeding (>80 cm3) in 6 cases (6.7%), although no tamponade, surgical intervention, or procedural mortality was seen. Patients with ICM who underwent a combined epi-endo ablation had improved freedom from VT compared with those who underwent endo-only ablation at 12 months (85% vs 56%; P =.03). In patients with NICM, no differences were seen between those who underwent epi-endo ablation and those who underwent endo-only ablation at 12 months (36% vs 33%; P = 1.0). In idiopathic VA, only 2 of 17 patients were successfully ablated from the epicardium. Conclusions: In this large tertiary single-center experience, complication rates are acceptably low and improved clinical outcomes were associated with epi-endo ablation in patients with ICM. Patients with NICM represent a growing referred population, although clinical recurrence remains high despite epicardial ablation. Epicardial ablation has a low yield in idiopathic VA.

Original languageEnglish
Pages (from-to)490-498
Number of pages9
JournalHeart Rhythm
Volume10
Issue number4
DOIs
StatePublished - Apr 2013
Externally publishedYes

Funding

FundersFunder number
National Heart, Lung, and Blood InstituteR01 HL084261

    Keywords

    • Ablation
    • Epicardial
    • Ventricular tachycardia

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