TY - JOUR
T1 - Eosinophilic granulomatous lymphadenopathy
T2 - Association with hyper-ige and eosinophilia
AU - Kaplinsky, Chaim
AU - Mor, Celia
AU - Cohen, Ian J.
AU - Goshen, Yaacov
AU - Zaizov, Rina
AU - Atias, Dina
PY - 1988
Y1 - 1988
N2 - Cervical lymph node enlargement is probably the most frequently detected childhood lymph-adenopathy. We report 2 cases of cervical lymphadenopathy in children associated with hyper-IgE and eosinophilia, displaying the features of necrotizing eosinophilic granulomatosis. Imrnu-nohistochemical analysis and a serological work-up failed to elucidate the underlying etiology. We would like to call the attention of physicians and pathologists to this unusual clinical picture, different from the fatal form of necrotizing eosinophilic granulomatosis, and we suggest a role for the eosinophils in the pathologic appearance of the lymph nodes..
AB - Cervical lymph node enlargement is probably the most frequently detected childhood lymph-adenopathy. We report 2 cases of cervical lymphadenopathy in children associated with hyper-IgE and eosinophilia, displaying the features of necrotizing eosinophilic granulomatosis. Imrnu-nohistochemical analysis and a serological work-up failed to elucidate the underlying etiology. We would like to call the attention of physicians and pathologists to this unusual clinical picture, different from the fatal form of necrotizing eosinophilic granulomatosis, and we suggest a role for the eosinophils in the pathologic appearance of the lymph nodes..
KW - Cervical lymphadenopathy
KW - Hyper-IgE
KW - Necrotizing eosinophilic granulomatosis
UR - http://www.scopus.com/inward/record.url?scp=0023771449&partnerID=8YFLogxK
U2 - 10.3109/15513818809041571
DO - 10.3109/15513818809041571
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AN - SCOPUS:0023771449
SN - 1551-3815
VL - 8
SP - 377
EP - 384
JO - Fetal and Pediatric Pathology
JF - Fetal and Pediatric Pathology
IS - 4
ER -