Eosinophilic granulomatous lymphadenopathy: Association with hyper-ige and eosinophilia

Chaim Kaplinsky*, Celia Mor, Ian J. Cohen, Yaacov Goshen, Rina Zaizov, Dina Atias

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Cervical lymph node enlargement is probably the most frequently detected childhood lymph-adenopathy. We report 2 cases of cervical lymphadenopathy in children associated with hyper-IgE and eosinophilia, displaying the features of necrotizing eosinophilic granulomatosis. Imrnu-nohistochemical analysis and a serological work-up failed to elucidate the underlying etiology. We would like to call the attention of physicians and pathologists to this unusual clinical picture, different from the fatal form of necrotizing eosinophilic granulomatosis, and we suggest a role for the eosinophils in the pathologic appearance of the lymph nodes..

Original languageEnglish
Pages (from-to)377-384
Number of pages8
JournalFetal and Pediatric Pathology
Issue number4
StatePublished - 1988


  • Cervical lymphadenopathy
  • Hyper-IgE
  • Necrotizing eosinophilic granulomatosis


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