Eosinophilia in newborn infants

L. Patel*, B. Garvey, S. Arnon, I. A.G. Roberts

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


To evaluate the clinical significance of eosinophilia in newborn infants, 261 admissions to the neonatal unit over a 12-month period were studied retrospectively; 33 babies with eosinophilia (> 1.0 x 109/1) were studied. Clinical and laboratory data for the first month of life were compared, where available, between gestational age-matched pairs with and without eosinophilia. Of the 33 babies with eosinophilia, 23 were > 26 weeks' gestation and all had age-matched controls; 10 were < 26 weeks' gestation but had no appropriate gestational age-matched controls. Babies > 26 weeks' gestation with eosinophilia had a significantly higher number of septic episodes than controls: 20 of 23 versus 4 of 23. All 10 babies < 26 weeks' gestation with eosinophilia developed sepsis. Infections with gram-negative organisms and necrotizing enterocolitis occurred only in babies who developed eosinopbilia. In 5 babies no cause for the eosinophilia was found. In conclusion, eosinophilia in the newborn is usually explainable and is most often associated with infection.

Original languageEnglish
Pages (from-to)797-801
Number of pages5
JournalActa Paediatrica, International Journal of Paediatrics
Issue number8
StatePublished - 1994
Externally publishedYes


  • Eosinophilia
  • Infection
  • Neonate
  • Premature infant


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