Enhanced electroretinogram in cats induced by exposure to mercury acetate

S. Gitter*, A. Pardo, N. Kariv, U. Yinon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The present study was undertaken in order to verify whether, and how, retinal functions are affected by subacute poisoning with organic mercury. Mercury acetate in various concentrations (0.025-0.25 mg/kg per day) was injected subcutaneously every second day to adult cats (N = 20) throughout a 2.5-4.0-week period. The electroretinogram (ERG) was recorded and the Hg2+ concentrations in the blood were determined. In nearly 90% of the intoxicated cats an enhanced electroretinogram (scotopic b-wave amplitude) was found as compared to its level in the normal control cats (N = 10). The latency of the ERG was found to be appropriately shorter, up to a maximal difference of nearly 20% in comparison to the controls. Hg2+ was present in the blood of the exposed cats during a 2.5-month period following the exposure. It is concluded that exposure to mercury acetate induces a permanent increase in the excitability level of the cat's retina.

Original languageEnglish
Pages (from-to)67-76
Number of pages10
Issue number1
StatePublished - Sep 1988


FundersFunder number
Committee for the Prevention and Research in Work, Ministry for Welfare and Work, Government of Israel
Tel Aviv University


    • Cats
    • Electroretinography
    • Mercury acetate
    • Subacute poisoning
    • Toxicological monitoring


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