Enhanced chloroplast-mitochondria crosstalk promotes ambient algal-H2 production

Tamar Elman, Thi Thu Hoai Ho, Yuval Milrad, Michael Hippler, Iftach Yacoby

Research output: Contribution to journalArticlepeer-review

Abstract

Microalgae are natural biocatalysts of hydrogen production. Their ability to convert solar energy to valuable compounds with minimal ecological footprint potentially places them as significant contributors to the clean-energy transition. Currently, algal hydrogen production, although promising, is not scalable because it is limited to oxygen-free conditions and is short-lived due to electron loss to other processes, mainly carbon fixation. Here, we show that a strain defective in thylakoid proton gradient regulation, Δpgr5, bypasses both challenges simultaneously, leading to a prolonged 12-day hydrogen production under ambient mixotrophic conditions in a 1-L setup. We report that Δpgr5 possess a repressed ability to fixate carbon and that this limitation is counterbalanced by an enhanced chloroplast-mitochondrion energetic exchange. This unique physiology supports the simplistic, yet robust and scalable, hydrogen production capability of Δpgr5.

Original languageEnglish
Article number100828
JournalCell Reports Physical Science
Volume3
Issue number4
DOIs
StatePublished - 20 Apr 2022

Keywords

  • bioengineering
  • chlamydomonas
  • green algae
  • hydrogen
  • mitochondria-chloroplast interaction
  • photosynthesis

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