TY - JOUR
T1 - Energy expenditure of patients with cystic fibrosis
AU - Vaisman, Nachum
AU - Pencharz, Paul B.
AU - Corey, Mary
AU - Canny, Gerard J.
AU - Hahn, Elizabeth
N1 - Funding Information:
Our study was designed to define the level of energy expenditure in patients with CF and to analyze the Supported in part by the Canadian Cystic Fibrosis Foundation. Dr. N. Vaisman holds a fellowship from The Foundation. Submitted for publication March 13, 1987; accepted May 22, 1987. Reprint requests: Dr. P. Pencharz, Division of Clinical Nutrition, Department of Paediatrics, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada M5G 1X8.
PY - 1987/10
Y1 - 1987/10
N2 - Resting energy expenditure was measured by open-circuit indirect calorimetry in 71 patients, aged 8.9 to 35.5 years, with cystic fibrosis who had no recent history of acute lung infection. Pulmonary function and nutritional status were studied simultaneously. In most patients, resting energy expenditure was above normal (range 95% to 153% of predicted values for age, sex, and weight as derived from the Harris Benedict equations), and was negatively correlated with pulmonary function (P<0.01) and nutritional status (P<0.01) when expressed as a percentage of body fat. Pulmonary status was positively correlated with nutritional status (P<0.01). We conclude that resting energy expenditure in patients with cystic fibrosis exceeds normal values and that the increase correlates with a deterioration in lung function and nutritional status.
AB - Resting energy expenditure was measured by open-circuit indirect calorimetry in 71 patients, aged 8.9 to 35.5 years, with cystic fibrosis who had no recent history of acute lung infection. Pulmonary function and nutritional status were studied simultaneously. In most patients, resting energy expenditure was above normal (range 95% to 153% of predicted values for age, sex, and weight as derived from the Harris Benedict equations), and was negatively correlated with pulmonary function (P<0.01) and nutritional status (P<0.01) when expressed as a percentage of body fat. Pulmonary status was positively correlated with nutritional status (P<0.01). We conclude that resting energy expenditure in patients with cystic fibrosis exceeds normal values and that the increase correlates with a deterioration in lung function and nutritional status.
UR - http://www.scopus.com/inward/record.url?scp=0023425424&partnerID=8YFLogxK
U2 - 10.1016/S0022-3476(87)80107-5
DO - 10.1016/S0022-3476(87)80107-5
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AN - SCOPUS:0023425424
SN - 0022-3476
VL - 111
SP - 496
EP - 500
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 4
ER -
