Endoscopy in pediatric polyposis syndromes: why, when and how

Shlomi Cohen*, Warren Hyer, Thomas Attard

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Single or multiple polyps are frequently encountered during colonoscopy among children and adolescents and may be indicative of hereditary polyposis syndrome (HPS). The management of children with single or multiple polyps is guided by the number of polyps, their distribution and the histological findings. Children with HPS carry a high risk of complications, including intestinal and extra-intestinal malignancies. The goals of surveillance in pediatric HPS are to treat symptoms, monitor the burden of polyps and prevent short- and long-term complications. Therefore, the management of children with HPS is based on therapeutic endoscopy. The strategy of therapeutic endoscopy is a careful assessment and characterization of the polyps and performing polypectomies using advanced endoscopic techniques. A multidisciplinary approach, comprising clinical, interventional endoscopy, cancer surveillance and support of familial and emotional aspects is essential in the management of children with HPS.

Original languageEnglish
Pages (from-to)255-263
Number of pages9
JournalEuropean Journal of Gastroenterology and Hepatology
Issue number3
StatePublished - 1 Mar 2024


  • children
  • colonoscopy
  • gastroscopy
  • polypectomy
  • polyposis syndromes


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