Endometrial receptivity in the light of modern assisted reproductive technologies

Y. Yaron, A. Botchan, A. Amit, M. R. Peyser, M. P. David, J. B. Lessing*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Objective: To review the different aspects of endometrial receptivity as it is reflected in the various modalities of modern assisted reproductive technologies. Design: The importance of endometrial receptivity and the factors that affect it such as the type of treatment, age, and ovarian function are discussed in this review. Novel approaches to determine receptivity such as Doppler ultrasonography and molecular biology are considered; assisted hatching is also discussed. Conclusions: Endometrial receptivity cannot, as yet, be directly assessed. Circumstantial evidence suggests that receptivity declines with age, is adversely affected by controlled ovarian hyperstimulation, and is possibly affected by ovarian function. Future studies will have to focus on molecular cell biology and physiology of the endometrium.

Original languageEnglish
Pages (from-to)225-232
Number of pages8
JournalFertility and Sterility
Issue number2
StatePublished - 1994
Externally publishedYes


  • ART
  • Endometrial receptivity
  • IVF
  • assisted hatching
  • implantation
  • oocyte donation


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