Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms

Richard S.E. Keefe; Philip D. Harvey; Mark F. Lenzenweger; Michael Davidson; Seth H. Apter; James Schmeidler; Richard C. Mohs; Kenneth L. Davis

doi:10.1016/0165-1781(92)90049-9

Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms

Richard S.E. Keefe
, Philip D. Harvey
, Mark F. Lenzenweger
, Michael Davidson
, Seth H. Apter
, James Schmeidler
, Richard C. Mohs
, Kenneth L. Davis

Clinical Departments

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

The factor structure of the Scale for the Assessment of Negative Symptoms (SANS) was examined in a confirmatory factor analysis that used the LISREL procedure. Four models of negative symptom factors were tested in 130 hospitalized schizophrenic patients. A three-factor model of diminished expression, social dysfunction, and disorganization generated by the authors yielded a superior fit to the data relative to the two-factor model of Liddle (1987b) and a unifactorial severity model. A four-factor model based on the original subscale formulation of the SANS failed to fit the data.

Original language	English
Pages (from-to)	153-165
Number of pages	13
Journal	Psychiatry Research
Volume	44
Issue number	2
DOIs	https://doi.org/10.1016/0165-1781(92)90049-9
State	Published - Nov 1992

Keywords

Deficit syndrome
Scale for the Assessment of Negative Symptoms
factor analysis

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10.1016/0165-1781(92)90049-9

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title = "Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms",

abstract = "The factor structure of the Scale for the Assessment of Negative Symptoms (SANS) was examined in a confirmatory factor analysis that used the LISREL procedure. Four models of negative symptom factors were tested in 130 hospitalized schizophrenic patients. A three-factor model of diminished expression, social dysfunction, and disorganization generated by the authors yielded a superior fit to the data relative to the two-factor model of Liddle (1987b) and a unifactorial severity model. A four-factor model based on the original subscale formulation of the SANS failed to fit the data.",

keywords = "Deficit syndrome, Scale for the Assessment of Negative Symptoms, factor analysis",

author = "Keefe, \{Richard S.E.\} and Harvey, \{Philip D.\} and Lenzenweger, \{Mark F.\} and Michael Davidson and Apter, \{Seth H.\} and James Schmeidler and Mohs, \{Richard C.\} and Davis, \{Kenneth L.\}",

year = "1992",

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AU - Keefe, Richard S.E.

AU - Harvey, Philip D.

AU - Lenzenweger, Mark F.

AU - Davidson, Michael

AU - Apter, Seth H.

AU - Schmeidler, James

AU - Mohs, Richard C.

AU - Davis, Kenneth L.

PY - 1992/11

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Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms

Abstract

Keywords

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