Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms

Richard S.E. Keefe; Philip D. Harvey; Mark F. Lenzenweger; Michael Davidson; Seth H. Apter; James Schmeidler; Richard C. Mohs; Kenneth L. Davis

doi:10.1016/0165-1781(92)90049-9

Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms

Richard S.E. Keefe, Philip D. Harvey, Mark F. Lenzenweger, Michael Davidson, Seth H. Apter, James Schmeidler, Richard C. Mohs, Kenneth L. Davis

Clinical Departments

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91 Scopus citations

Abstract

The factor structure of the Scale for the Assessment of Negative Symptoms (SANS) was examined in a confirmatory factor analysis that used the LISREL procedure. Four models of negative symptom factors were tested in 130 hospitalized schizophrenic patients. A three-factor model of diminished expression, social dysfunction, and disorganization generated by the authors yielded a superior fit to the data relative to the two-factor model of Liddle (1987b) and a unifactorial severity model. A four-factor model based on the original subscale formulation of the SANS failed to fit the data.

Original language	English
Pages (from-to)	153-165
Number of pages	13
Journal	Psychiatry Research
Volume	44
Issue number	2
DOIs	https://doi.org/10.1016/0165-1781(92)90049-9
State	Published - Nov 1992

Keywords

Deficit syndrome
Scale for the Assessment of Negative Symptoms
factor analysis

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title = "Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms",

abstract = "The factor structure of the Scale for the Assessment of Negative Symptoms (SANS) was examined in a confirmatory factor analysis that used the LISREL procedure. Four models of negative symptom factors were tested in 130 hospitalized schizophrenic patients. A three-factor model of diminished expression, social dysfunction, and disorganization generated by the authors yielded a superior fit to the data relative to the two-factor model of Liddle (1987b) and a unifactorial severity model. A four-factor model based on the original subscale formulation of the SANS failed to fit the data.",

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AU - Keefe, Richard S.E.

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AU - Davidson, Michael

AU - Apter, Seth H.

AU - Schmeidler, James

AU - Mohs, Richard C.

AU - Davis, Kenneth L.

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Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms

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Keywords

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