We report an emergence and increase in poliovirus type 2 detection via routine wastewater surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April and July 2022. Sequencing showed genetic linkage among isolates and accumulation of mutations over time, with two isolates defined as vaccine-derived polioviruses (VDPV). This demonstrates the emergence and potential circulation of type 2 VDPV in a high-income country with high vaccine coverage and underscores the importance of routine wastewater surveillance during the polio eradication.
|State||Published - 1 Sep 2022|
- Environmental surveillance
- Polio type 2 (PV2)
- Vaccine Derived Polio Virus (VDPV)
- Whole Genome Sequencing (WGS)