Embryonal reduction using transvaginal saline injection in a sextuplet pregnancy after ovulation induction with human menopausal gonadotropin

Yuval Yaron, Amnon Botchan, Joseph B. Lessing, M. Reuben Peyser*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A sextuplet pregnancy occurred in a first treatment cycle of ovulation induction with human menopausal gonadotropins. The serum 17‐β‐estradiol concentration was 1245 pg/ml on the day of human chorionic gonadotropin administration. Embryonal reduction of four fetuses was carried out at nine weeks gestation using a transvaginal ultrasound‐guided approach. Under general anesthesia, a 16‐gauge in vitro fertilization needle was introduced through the posterior fornix and uterine wall, into the nearest gestational sac. The embryo was penetrated and 0.9% saline solution was injected until disintegration was noted, and confirmed by a lack of pulse for more than two minutes. The same procedure was applied to the three embryos in closest proximity to the needle. The patient delivered healthy twins in the 34th week of gestation after having had pre‐term contractions for two weeks. 1993 Acta Obstet Gynecol Scand

Original languageEnglish
Pages (from-to)578-580
Number of pages3
JournalActa Obstetricia et Gynecologica Scandinavica
Volume72
Issue number7
DOIs
StatePublished - Oct 1993

Keywords

  • embryonal reduction
  • multiple pregnancy
  • ovulation induction

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