@article{3d739d13132c4173b52fd84d047e2af7,
title = "Elucidating mechanisms underlying robustness of morphogen gradients",
abstract = "Morphogen gradients play a pivotal role in most phases of developmental patterning. To ensure proper patterning, reproducible gradients are established under diverse environmental conditions and genetic backgrounds. We refer to the capacity to buffer fluctuations in gene dosage or environmental conditions as 'robustness'. By theoretical analysis of mechanisms that facilitate robustness, it is possible to unravel the machinery responsible for generating the spatial distribution of morphogens.",
keywords = "BMP, Decapentaplegic, Dpp, Shortened gastrulation, Sog, Tld, Tolloid, bone morphogenetic protein",
author = "Avigdor Eldar and Shilo, \{Ben Zion\} and Naama Barkai",
note = "Funding Information: This work was supported by the Clore Center for Biological Physics, the Israel Science Foundation (B-Z Shilo), the Israel Science Foundation (N Barkai), and the Minerva Foundation (N Barkai). B-Z Shilo is an incumbent of the Hilda and Cecil Lewis professorial chair in Molecular Genetics. N Barkai is the incumbent of the Soretta and Henry Shapiro career development chair.",
year = "2004",
month = aug,
doi = "10.1016/j.gde.2004.06.009",
language = "אנגלית",
volume = "14",
pages = "435--439",
journal = "Current Opinion in Genetics and Development",
issn = "0959-437X",
publisher = "Elsevier Ltd.",
number = "4",
}