Elevated plasma immunoreactive β-endorphin in anorexia nervosa

R. Tepper; A. Weizman; A. Apter; S. Tyano; Y. Beyth

doi:10.1097/00002826-199210000-00006

Elevated plasma immunoreactive β-endorphin in anorexia nervosa

R. Tepper, A. Weizman^*, A. Apter, S. Tyano, Y. Beyth

^*Corresponding author for this work

Geha Mental Health Center

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Basal morning plasma levels of immunoreactive-β-endorphin (ir-β-EP), and 17-β estradiol (E₂) were assessed in 25 adolescents with anorexia nervosa (AN) in comparison to 24 healthy controls. All subjects were drug free for at least 6 weeks. The mean plasma level of ir-β-EP was significantly higher (84%) in the AN patients when compared with the control subjects. The elevated plasma ir-β-EP may be relevant to the suppression of appetite, tolerance of fasting, and to the hypothalamic hypogonadism in AN.

Original language	English
Pages (from-to)	387-391
Number of pages	5
Journal	Clinical Neuropharmacology
Volume	15
Issue number	5
DOIs	https://doi.org/10.1097/00002826-199210000-00006
State	Published - 1992
Externally published	Yes

Keywords

Anorexia nervosa
Hypogonadism
Starvation
Stress
β-Endorphin

Access to Document

10.1097/00002826-199210000-00006

Cite this

@article{a253b76b4c9241919a126883f62f86b2,

title = "Elevated plasma immunoreactive β-endorphin in anorexia nervosa",

abstract = "Basal morning plasma levels of immunoreactive-β-endorphin (ir-β-EP), and 17-β estradiol (E2) were assessed in 25 adolescents with anorexia nervosa (AN) in comparison to 24 healthy controls. All subjects were drug free for at least 6 weeks. The mean plasma level of ir-β-EP was significantly higher (84%) in the AN patients when compared with the control subjects. The elevated plasma ir-β-EP may be relevant to the suppression of appetite, tolerance of fasting, and to the hypothalamic hypogonadism in AN.",

keywords = "Anorexia nervosa, Hypogonadism, Starvation, Stress, β-Endorphin",

author = "R. Tepper and A. Weizman and A. Apter and S. Tyano and Y. Beyth",

year = "1992",

doi = "10.1097/00002826-199210000-00006",

language = "אנגלית",

volume = "15",

pages = "387--391",

journal = "Clinical Neuropharmacology",

issn = "0362-5664",

publisher = "Lippincott Williams and Wilkins",

number = "5",

}

TY - JOUR

T1 - Elevated plasma immunoreactive β-endorphin in anorexia nervosa

AU - Tepper, R.

AU - Weizman, A.

AU - Apter, A.

AU - Tyano, S.

AU - Beyth, Y.

PY - 1992

Y1 - 1992

N2 - Basal morning plasma levels of immunoreactive-β-endorphin (ir-β-EP), and 17-β estradiol (E2) were assessed in 25 adolescents with anorexia nervosa (AN) in comparison to 24 healthy controls. All subjects were drug free for at least 6 weeks. The mean plasma level of ir-β-EP was significantly higher (84%) in the AN patients when compared with the control subjects. The elevated plasma ir-β-EP may be relevant to the suppression of appetite, tolerance of fasting, and to the hypothalamic hypogonadism in AN.

AB - Basal morning plasma levels of immunoreactive-β-endorphin (ir-β-EP), and 17-β estradiol (E2) were assessed in 25 adolescents with anorexia nervosa (AN) in comparison to 24 healthy controls. All subjects were drug free for at least 6 weeks. The mean plasma level of ir-β-EP was significantly higher (84%) in the AN patients when compared with the control subjects. The elevated plasma ir-β-EP may be relevant to the suppression of appetite, tolerance of fasting, and to the hypothalamic hypogonadism in AN.

KW - Anorexia nervosa

KW - Hypogonadism

KW - Starvation

KW - Stress

KW - β-Endorphin

UR - http://www.scopus.com/inward/record.url?scp=0026783480&partnerID=8YFLogxK

U2 - 10.1097/00002826-199210000-00006

DO - 10.1097/00002826-199210000-00006

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0026783480

SN - 0362-5664

VL - 15

SP - 387

EP - 391

JO - Clinical Neuropharmacology

JF - Clinical Neuropharmacology

IS - 5

ER -

Elevated plasma immunoreactive β-endorphin in anorexia nervosa

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this