Elevated levels of serum creatine kinase induced by hyponatraemia

Ilan Goldenberg, Michael Jonas, Michael Thaler, Ehud Grossman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Elevated serum creatine kinase levels are one of the major criteria for the diagnosis of myocardial injury. Noncardiac causes such as muscular and brain damage may also be associated with elevated serum creatine kinase levels. Hyponatremia may induce increased serum creatine kinase in association with rhabdomyolysis or with hypothyroidism. A patient is described where three episodes of hyponatraemia not associated with rhabdomyolysis or hypothyroidism induced transient elevations of serum creatine kinase levels. The association between hyponatraemia and elevated creatine kinase levels should be emphasized to prevent erroneous diagnosis of myocardial injury.

Original languageEnglish
Pages (from-to)511-512
Number of pages2
JournalPostgraduate Medical Journal
Issue number862
StatePublished - 1997
Externally publishedYes


  • Creatine kinase
  • Hyponatraemia
  • Sodium


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