Electrostatics of non-neutral biological microdomains

J. Cartailler, Z. Schuss, D. Holcman

Research output: Contribution to journalArticlepeer-review

Abstract

Voltage and charge distributions in cellular microdomains regulate communications, excitability, and signal transduction. We report here new electrical laws in a biological cell, which follow from a nonlinear electro-diffusion model. These newly discovered laws derive from the geometrical cell-membrane properties, such as membrane curvature, volume, and surface area. The electro-diffusion laws can now be used to predict and interpret voltage distribution in cellular microdomains such as synapses, dendritic spine, cilia and more.

Original languageEnglish
Article number11269
JournalScientific Reports
Volume7
Issue number1
DOIs
StatePublished - 1 Dec 2017

Fingerprint

Dive into the research topics of 'Electrostatics of non-neutral biological microdomains'. Together they form a unique fingerprint.

Cite this