Electrolyte changes in mesothelioma

Joseph Ribak*, Alan Herman, Irving J. Selikoff

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Little has been reported concerning electrolyte changes among patients with mesothelioma. Two studies have suggested that hyponatraemia is particularly common among them and should lead to suspicion of inappropriate secretion of antidiuretic hormone in those patients (Perks et al. 1979; Siafakas et al. 1984). We reviewed serum electrolyte changes in three groups of patients: 48 cases of pleural mesothelioma, 89 of peritoneal mesothelioma, associated with asbestos exposure, and 149 of asbestosis. Five of 48 (10.4%) patients with pleural mesothelioma, 17 of 89 (19.1%) with peritoneal mesothelioma, and 23 of 149 (15.4%) patients with asbestosis without mesothelioma, had hyponatraemia. No statistically significant difference among the groups was found. These findings do not support the proposal that hyponatraemia is unusually common when mesothelioma is present, at least not among patients whose neoplasms are related to asbestos exposure.

Original languageEnglish
Pages (from-to)280-282
Number of pages3
JournalBritish Journal of Diseases of the Chest
Issue numberC
StatePublished - 1986
Externally publishedYes


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