Efficacy of ciprofloxacin against Leptospira interrogans serogroup icterohaemorrhagiae

I. Shalit, A. Barnea, A. Shahar

Research output: Contribution to journalArticlepeer-review

Abstract

Ciprofloxacin activity against Leptospira interrogans serogroup icterohaemorrhagiae was studied in vitro and in an animal model. The MBC of ciprofloxacin was 0.6 μg/ml. Three of three Syrian hamsters died 8 to 9 days after intraperitoneal challenge with 106 leptospires. In contrast, five of six animals given ciprofloxacin 3 or 5 days after challenge survived.

Original languageEnglish
Pages (from-to)788-789
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Volume33
Issue number5
DOIs
StatePublished - 1989

Fingerprint

Dive into the research topics of 'Efficacy of ciprofloxacin against Leptospira interrogans serogroup icterohaemorrhagiae'. Together they form a unique fingerprint.

Cite this