Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-to-head, randomised controlled trial

Roy Fleischmann, Eduardo Mysler, Stephen Hall, Alan J. Kivitz, Robert J. Moots, Zhen Luo, Ryan DeMasi, Koshika Soma, Richard Zhang, Liza Takiya, Svitlana Tatulych, Christopher Mojcik, Sriram Krishnaswami, Sujatha Menon, Josef S. Smolen, Luthando Adams, Mahmood M. Ally, Maria C. du Plooy, Ingrid C. Louw, Savithree NayiagerChristoffel B. Nel, Debra Nel, Helmuth Reuter, Ahmed S. Soloman, Catherine E. Spargo, Stephen Hall, Maureen Rischmueller, Shunil D. Sharma, Robert K. Will, Peter P. Youssef, Caroline Arroyo, Rosario P. Baes, Roger B. Dulos, Llewellyn T. Hao, Allan E. Lanzon, Juan Javier T. Lichauco, Jill H. Mangubat, Edgar B. Ramiterre, Bernadette Heizel M. Reyes, Perry P. Tan, Jung Yoon Choe, Young Mo Kang, Seong Ryul Kwon, Sang Heon Lee, Shin Seok Lee, Dae Hyun Yoo, Hsiao Yi Lin, Shue Fen Luo, Shih Tzu Tsai, Wen Chan Tsai, Jui Cheng Tseng, Cheng Chung C. Wei, Paijit Asavatanabodee, Kanokrat Nantiruj, Surasak Nilganuwong, Parichat Uea-Areewongsa, Ljubinka Bozic Majstorovic, Suada Mulic Bacic, Anastas Z. Batalov, Gabriela Georgieva-Slavcheva, Mariyana Mihailova, Nikolay G. Nikolov, Dimitar P. Penev, Yuliy A. Spasov, Krasimira Stanimirova, Stoyan Todorov, Antoaneta R. Toncheva, Nadezhda Yordanova, Zdenka Mosterova, Libor Novosad, Leona Prochazkova, Helena Stehlikova, Zuzana Stejfova, Natalia Kiseleva, Lea Pank, Triin Savi, Balbir Gurman Alexandra, Howard Amital, Dror Mevorach, Itzhak A. Rosner, Anna Mihailova, Evija Stumbra-Stumberga, Vida Basijokiene, Virginija Lietuvininkiene, Dalia Unikiene, Jan Brzezicki, Anna M. Dudek, Maria B. Glowacka-Kulesz, Barbara Grabowicz-Wasko, Sabina Hajduk-Kubacka, Joanna Hilt, Pawel Hrycaj, Slawomir Jeka, Renata Kolasa, Marek Krogulec, Hanna Mastalerz, Anna Olak-Popko, Elzbieta Owczarek, Zofia Ruzga, Alina Walczak, Codrina I. Ancuta, Ioan Ancuta, Andra R. Balanescu, Florian Berghea, Silvia Bojin, Mihaela A.Ianuli Arvunescu, Ruxandra M. Ionescu, Eugenia Mociran, Mariana Pavel, Simona Rednic, Adriana Voie, Carmen M. Zainea, Olga V. Bugrova, Alexander Demin, Olga B. Ershova, Inna A. Gavrisheva, Diana G. Krechikova, Gennady V. Kuropatkin, Irina M. Marusenko, Irina V. Menshikova, Sergey M. Noskov, Andrey P. Rebrov, Svetlana A. Smakotina, Sergey S. Yakushin, Evgeny Zhilyaev, Juan Jose Amarelo Ramos, Francisco Javier Blanco Garcia, Antonio Fernandez Nebro, Silvia Perez Esteban, Juan Miguel Sanchez Burson, Raimon Sanmarti Sala, Sebnem Ataman, Sami Hizmetli, Omer Kuru, Karen M. Douglas, Paul Emery, Robert J. Moots, Voon H. Ong, Thomas P. Sheeran, Rafat Y. Faraawi, Clode Lessard, Carlos Abud Mendoza, Hilario Ernesto Avila-Armengol, Francisco I.Avila Zapata, Fedra Consuelo Irazoque-Palazuelos, Marco Antonio Maradiaga Cecena, Cesar F. Pacheco-Tena, Juan C. Rizo-Rodriguez, Isaura M. Rodriguez-Torres, Jacob A. Aelion, Barbara A. Caciolo, James M. Calmes, Prem Chatpar, Nimesh Dayal, Alex De Jesus, Ara H. Dikranian, Erdal Diri, Michael J. Fairfax, Ira F. Fenton, Roy M. Fleischmann, Norman B. Gaylis, Ronald L. George, Dale G. Halter, Paul Hernandez, Susan A. Hole, Antony C. Hou, John P. Huff, Suzanne Kafaja, Alastair C. Kennedy, Howard Kenney, Steven C. Kimmel, Brian S. Kirby, Alan J. Kivitz, Clarence W. Legerton, Stephen M. Lindsey, Jyothi R. Mallepalli, Steven D. Mathews, Samy K. Metyas, Wesley T. Mizutani, Sabeen Najam, Joao M. Nascimento, Shirley W. Pang, Rakesh C. Patel, Jeffrey E. Poiley, Carlos E. Ramirez, Riteesha Reddy, Qaiser Rehman, William M. Schnitz, Craig D. Scoville, William J. Shergy, Joel C. Silverfield, Atul K. Singhal, Yvonne R. Smallwood-Sherrer, Suthin N. Songcharoen, Michael T. Stack, William Stohl, Tien I.K. Su, James Udell, Saleem Waraich, Charles E. Weidmann, Nathan Wei, Craig W. Wiesenhutter, Anne E. Winkler, Karen E. Zagar, Alberto Berman, Eduardo F. Mysler, Rodolfo A.Pardo Hidalgo, Horacio O. Venarotti, Irmgadt Annelise Goecke Sariego, Renato E.Jimenez Calabresse, Juan Ignacio Vargas Ruiz-Tagle, Luis Fernando M.Bellatin Vargas, Alfredo E. Berrocal, Manuel Gustavo Leon Portocarrero, Felix Jesus, Romero Pena

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