Similarly to the results reported in pregnancy and during oral contraceptive use, estrogen replacement therapy (ERT) had a lowering effect on serum immunoglobulins (IgG, IgA, IgM) of 20 postmenopausal women with a mean age of 52.2 years, in parallel with an increase in the blood values of estradiol (E2). The clinical implications of this phenomenon warrant the study on a bigger series and during a longer period of time. It is recommended to use with precaution the ERT in women with known defects in the immunologic system. A study on the effect of the new transdermal therapeutic system (Estraderm, TTS, Ciba) on the immunoglobulins is in course.
|Translated title of the contribution||The lowering effect of estrogen replacement therapy on immunoglobulins of menopausal women|
|Number of pages||3|
|Journal||Revue Francaise de Gynecologie et d'Obstetrique|
|State||Published - 1990|