Effects of long-term treatment with bromocriptine on pituitary prolactinoma in a male

D. Ayalon, N. Eckstein, Z. T. Homonnai, G. F. Paz, A. Eshel, I. Reider

Research output: Contribution to journalArticlepeer-review

Abstract

Poor surgical results are obtained when operating on large prolactinomas, especially when an extrasellar growth is demonstrated. Several groups have reported tumor regression following bromocriptine treatment. A case report is presented of a young hyperprolactinemic man with a large pituitary adenoma with suprasellar extension, normal visual fields, decreased libido, impotence, hypogonadism and azoospermia. This man was treated with high doses of bromocriptine for a period of 5 months. A significant improvement of potency libido and sperm concentration associated with radiological evidence of a marked reduction of tumor size was noted following suppressive treatment with this ergot alkaloid.

Original languageEnglish
Pages (from-to)481-485
Number of pages5
JournalInternational Journal of Gynecology and Obstetrics
Volume20
Issue number6
DOIs
StatePublished - Dec 1982

Keywords

  • Azoospermia
  • Bromocriptine
  • Hyperprolactinemia
  • Hypogonadism
  • Impotence
  • Pituitary prolactinoma

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