Effects of coronary occlusion on high-frequency content of the epicardial electrogram and body surface electrocardiogram

V. Mor-Avi, B. Shargorodsky, S. Abboud, S. Laniado, S. Akselrod

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

The very high-frequency content (150 to 250 Hz) of epicardial electrogram waveforms was studied in 19 anesthetized dogs subjected to occlusion of left anterior descending coronary artery. Computer techniques of digital averaging and digital band-pass filtering were applied. Signals were obtained from epicardial electrodes placed in the ischemic left ventricular region and on the noninjured right ventricular surface, and from the body surface electrocardiogram. All recordings were made simultaneously before, during, and after coronary occlusion and subjected to the same analysis. The waveforms obtained from the ischemic left ventricular region showed a considerable decrease in high-frequency content, while those obtained from the noninjured right ventricular surface remained unchanged. The results correlated with the appearance of a zone of reduced amplitude in the body surface high-frequency QRS complex. Therefore, this macroscopic phenomenon measured noninvasively from the body surface is explained by local reduction of high-frequency activity in the ischemic region of the myocardium.

Original languageEnglish
Pages (from-to)237-243
Number of pages7
JournalCirculation
Volume76
Issue number1
DOIs
StatePublished - 1987

Fingerprint

Dive into the research topics of 'Effects of coronary occlusion on high-frequency content of the epicardial electrogram and body surface electrocardiogram'. Together they form a unique fingerprint.

Cite this