Effects of antipsychotic drugs on memory functions of schizophrenic patients

N. Eitan; Y. Levin; E. Ben‐Artzi; A. Levy; M. Neumann

doi:10.1111/j.1600-0447.1992.tb01446.x

Effects of antipsychotic drugs on memory functions of schizophrenic patients

N. Eitan, Y. Levin^*, E. Ben‐Artzi, A. Levy, M. Neumann

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

In this research we investigated the effects of 4 antipsychotic drugs with different anticholinergic components on different memory functions of schizophrenic patients. Drugs were administrated in cumulative doses and memory was tested 90 min after each drug was administered. The results show that chlorpromazine and thioridazine impaired short‐term verbal memory after 6 h of sequential administration. Trifluoperazine and haloperidol improved short‐term verbal memory from the third to the fifth administration. Immediate memory, long‐term memory and visual short‐term memory were not impaired by any drug.

Original language	English
Pages (from-to)	74-76
Number of pages	3
Journal	Acta Psychiatrica Scandinavica
Volume	85
Issue number	1
DOIs	https://doi.org/10.1111/j.1600-0447.1992.tb01446.x
State	Published - Jan 1992
Externally published	Yes

Keywords

Key words:
antipsychotic drug
memory
schizophrenia

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10.1111/j.1600-0447.1992.tb01446.x

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AU - Levin, Y.

AU - Ben‐Artzi, E.

AU - Levy, A.

AU - Neumann, M.

PY - 1992/1

Y1 - 1992/1

N2 - In this research we investigated the effects of 4 antipsychotic drugs with different anticholinergic components on different memory functions of schizophrenic patients. Drugs were administrated in cumulative doses and memory was tested 90 min after each drug was administered. The results show that chlorpromazine and thioridazine impaired short‐term verbal memory after 6 h of sequential administration. Trifluoperazine and haloperidol improved short‐term verbal memory from the third to the fifth administration. Immediate memory, long‐term memory and visual short‐term memory were not impaired by any drug.

AB - In this research we investigated the effects of 4 antipsychotic drugs with different anticholinergic components on different memory functions of schizophrenic patients. Drugs were administrated in cumulative doses and memory was tested 90 min after each drug was administered. The results show that chlorpromazine and thioridazine impaired short‐term verbal memory after 6 h of sequential administration. Trifluoperazine and haloperidol improved short‐term verbal memory from the third to the fifth administration. Immediate memory, long‐term memory and visual short‐term memory were not impaired by any drug.

KW - Key words:

KW - antipsychotic drug

KW - memory

KW - schizophrenia

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ER -

Effects of antipsychotic drugs on memory functions of schizophrenic patients

Abstract

Keywords

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