Effect of verapamil on platelet surface ultrastructure and calcium content

M. Djaldetti; R. Gilgal; P. Fishman; I. Zahavi

doi:10.1159/000205688

Effect of verapamil on platelet surface ultrastructure and calcium content

M. Djaldetti^*, R. Gilgal, P. Fishman, I. Zahavi

^*Corresponding author for this work

Clinical Departments

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Abstract

The effect of verapamil on the surface ultrastructure and calcium content of human platelets was studied by scanning electron microscopy and X-ray microanalysis. The results showed that the drug prevents platelet pseudopodia formation and causes a dose-dependent inhibition of platelet calcium concentration. The significance of these findings in the explanation of the inhibitory effect of verapamil on platelet aggregation is discussed.

Original language	English
Pages (from-to)	41-43
Number of pages	3
Journal	Acta Haematologica
Volume	79
Issue number	1
DOIs	https://doi.org/10.1159/000205688
State	Published - 1988

Keywords

Platelet calcium content
Scanning electron microscopy
Verapamil
X-ray microanalysis

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10.1159/000205688

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KW - Scanning electron microscopy

KW - Verapamil

KW - X-ray microanalysis

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Effect of verapamil on platelet surface ultrastructure and calcium content

Abstract

Keywords

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