TY - JOUR
T1 - Effect of venous stasis on the consolidation of fractures
AU - Nerubay, Jacobo
AU - Katznelson, Alexander
AU - Tadmor, Amnon
PY - 1980/6
Y1 - 1980/6
N2 - In an experimental study of 60 rabbits (120 preparations) in which a bilateral fibular osteotomy was performed, a group of 40 rabbits had ligation of the vena cava, and a group of 20 rabbits were used as controls. The results were evaluated by microscopic study by H&E, PAS and Alcian Blue staining and showed that venous stasis accelerates the process of fracture healing by increasing fibroblastic and osteoblastic proliferation and bone production. The effects of changes in pH, and concentrations of oxygen and carbon dioxide are suggested as the factors that modify the mechanism of osteogenesis, and greater quantities of mucopolysaccharide substances were observed at the fracture site in the group with venous stasis.
AB - In an experimental study of 60 rabbits (120 preparations) in which a bilateral fibular osteotomy was performed, a group of 40 rabbits had ligation of the vena cava, and a group of 20 rabbits were used as controls. The results were evaluated by microscopic study by H&E, PAS and Alcian Blue staining and showed that venous stasis accelerates the process of fracture healing by increasing fibroblastic and osteoblastic proliferation and bone production. The effects of changes in pH, and concentrations of oxygen and carbon dioxide are suggested as the factors that modify the mechanism of osteogenesis, and greater quantities of mucopolysaccharide substances were observed at the fracture site in the group with venous stasis.
UR - http://www.scopus.com/inward/record.url?scp=0018827924&partnerID=8YFLogxK
U2 - 10.1097/00005373-198006000-00014
DO - 10.1097/00005373-198006000-00014
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AN - SCOPUS:0018827924
SN - 0022-5282
VL - 20
SP - 513
EP - 517
JO - Journal of Trauma and Acute Care Surgery
JF - Journal of Trauma and Acute Care Surgery
IS - 6
ER -