@article{9d8486690bea424bb9e7c84764f8bb79,
title = "Effect of total lymphoid irradiation (TLI) on the primary and secondary antibody response to sheep red blood cells",
abstract = "The effect of total lymphoid irradiation (TLI) on the primary and secondary hemagglutinin response to sheep red blood cells (SRBC) was studied in BALB/c mice. The primary response was eliminated for 1 month and began to return by Day 44. The latter response was IgM, and the IgG response did not return until approximately 200 days after TLI. The prolonged immunosuppression required inclusion of the thymus in the radiation field. Mice treated with single-dose whole-body irradiation (WBI) regained a normal IgG response within 28 days after irradiation. Immunization of mice prior to treatment with TLI or WBI resulted in a vigorous IgG response when mice were boosted 1 month after irradiation.",
author = "Israel Zan-Bar and Shimon Slavin and Samuel Strober",
note = "Funding Information: {\textquoteright} Supported by National Institutes of Health Grants AI 11313 and CA17004 and by the Howard Hughes Medical Institute. il Postdoctoral Fellow of the Arthritis Foundation. Present address: Department of Cell Biology. Weizmann Institute of Science, Rehovot, Israel. s Recipient of Fogarty International Fellowship (5FOS TW 02227). Present address: Department of Medicine A, Hadassah, University Hospital, Jerusalem, Israel. 4 Investigator, Howard Hughes Medical Institute. s Abbreviations used: TLI, total lymphoid irradiation; PHA phytohemagglutinin; MLR, allogeneic lymphocytes; GVHD, graft versus host disease; BSA, bovine serum albumin; SRBC, sheep red blood ceils: 2-ME, 2-mercaptoethanol; WBI, whole-body irradiation.",
year = "1979",
month = jun,
doi = "10.1016/0008-8749(79)90372-1",
language = "אנגלית",
volume = "45",
pages = "167--174",
journal = "Cellular Immunology",
issn = "0008-8749",
publisher = "Academic Press Inc.",
number = "1",
}