Effect of preanaesthetic medication on anaesthesia with ici 35 868

L. P. Briggs*, M. Bahar, H. T.B. Beers, R. S.J. Clarke, J. W. Dundee, P. J. Wright, D. M. Mcauley, M. P. O'neill

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The effect of three commonly used premcdicants and a control on anaesthesia with ICI 35 868 is described Two randomized studies were performed-one a group study of induction characteristics at 2mgkg-1 and the other a detailed study in patients undergoing minor gynaecological surgery with an induction dose of 1.5mgkg-1 and maintenance with incremental doses plus 66% nitrous oxide in oxygen Premedication had little effect on the already good induction characteristics. Only heavy opiate premedication produced reliable induction at 1 5 mg kg-1, but with an increase in side-effects Diazepam appears to be the premedicant of choice, although the overall frequency of pain on injection has not been affected by premedication.

Original languageEnglish
Pages (from-to)303-306
Number of pages4
JournalBritish Journal of Anaesthesia
Issue number3
StatePublished - Mar 1982
Externally publishedYes


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