Effect of preanaesthetic medication on anaesthesia with ici 35 868

L. P. Briggs; M. Bahar; H. T.B. Beers; R. S.J. Clarke; J. W. Dundee; P. J. Wright; D. M. Mcauley; M. P. O'neill

doi:10.1093/bja/54.3.303

Effect of preanaesthetic medication on anaesthesia with ici 35 868

L. P. Briggs^*, M. Bahar, H. T.B. Beers, R. S.J. Clarke, J. W. Dundee, P. J. Wright, D. M. Mcauley, M. P. O'neill

^*Corresponding author for this work

Queen's University Belfast

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The effect of three commonly used premcdicants and a control on anaesthesia with ICI 35 868 is described Two randomized studies were performed-one a group study of induction characteristics at 2mgkg^-1 and the other a detailed study in patients undergoing minor gynaecological surgery with an induction dose of 1.5mgkg^-1 and maintenance with incremental doses plus 66% nitrous oxide in oxygen Premedication had little effect on the already good induction characteristics. Only heavy opiate premedication produced reliable induction at 1 5 mg kg^-1, but with an increase in side-effects Diazepam appears to be the premedicant of choice, although the overall frequency of pain on injection has not been affected by premedication.

Original language	English
Pages (from-to)	303-306
Number of pages	4
Journal	British Journal of Anaesthesia
Volume	54
Issue number	3
DOIs	https://doi.org/10.1093/bja/54.3.303
State	Published - Mar 1982
Externally published	Yes

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abstract = "The effect of three commonly used premcdicants and a control on anaesthesia with ICI 35 868 is described Two randomized studies were performed-one a group study of induction characteristics at 2mgkg-1 and the other a detailed study in patients undergoing minor gynaecological surgery with an induction dose of 1.5mgkg-1 and maintenance with incremental doses plus 66% nitrous oxide in oxygen Premedication had little effect on the already good induction characteristics. Only heavy opiate premedication produced reliable induction at 1 5 mg kg-1, but with an increase in side-effects Diazepam appears to be the premedicant of choice, although the overall frequency of pain on injection has not been affected by premedication.",

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Effect of preanaesthetic medication on anaesthesia with ici 35 868

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