Effect of Phytohemagglutinin on Hemolytic Plaque Formation by Rat Lymphoid Cells

Edgar Pick*, Joseph D. Feldman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Rat TD, splenic, and thymic cells, with or without prior exposure to SRC in vivo, yielded reduced numbers of PFC when the lymphoid cells were incubated for 96 hours in a medium containing PHA-M during 1-4 days of the incubation. The infusion of PHA-P into rats 3 and 2 days before and after the intravenous injection of SRC resulted in a diminution of PFC in the spleen. The administration of PHA-P to rats 1 day before, at the time of, or 1 day after antigen injection resulted in an increase of PFC in the spleen.

Original languageEnglish
Pages (from-to)524-526
Number of pages3
JournalExperimental Biology and Medicine
Volume127
Issue number2
DOIs
StatePublished - Feb 1968
Externally publishedYes

Funding

FundersFunder number
U.S. Public Health ServiceAI-7007

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