Effect of maternal congenital heart defects on labor and delivery outcome: A population-based study

Rakefet Sidlik, Eyal Sheiner*, Amalia Levy, Arnon Wiznitzer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Objective. The primary objective of this study was to characterize the delivery outcome of parturients with congenital heart defects (CHD), from maternal and from neonatal perspectives. Study design. A retrospective population-based study was conducted, covering a 13-year period (1989-2002) with an aggregate of 151 487 deliveries of all women with and without CHD. Maternal demographics, obstetrical and medical history, delivery outcome, and neonatal outcome were drawn from a computerized perinatal database. Results. Sixty-seven women with CHD had 156 deliveries. The severity of CHD, based on the New York Heart Association (NYHA) classification, was I or II in 99.1% of the deliveries. CHD patients had significantly higher rates of labor induction and neonatal malformations. Maternal CHD was discovered as an independent risk factor associated with neonatal malformations (OR 2.10, 95% CI 1.18-3.72). No significant differences were noted between women with CHD and the controls regarding maternal morbidities and Apgar scores. Conclusions. The labor outcome of CHD patients with NYHA classification I and II resembles that of non-CHD women in a tertiary center setting. Neonates of CHD mothers have higher rates of congenital malformations even among asymptomatic or mildly symptomatic mothers. A careful sonographic follow-up is warranted among all pregnancies of CHD patients.

Original languageEnglish
Pages (from-to)211-216
Number of pages6
JournalJournal of Maternal-Fetal and Neonatal Medicine
Issue number3
StatePublished - 2007
Externally publishedYes


  • Congenital heart disease
  • High risk pregnancy
  • Maternal heart disease
  • Neonatal malformations
  • Neonatal outcome


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