Effect of maternal body mass index on cord blood erthropoietin concentrations

S. Barak, F. B. Mimouni, R. Stern, N. Cohen, R. Marom*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objective:To examine the hypothesis that maternal body mass index (BMI) (an index of maternal adiposity) correlates with cord blood concentrations of erythropoietin (EPO).Study design:Cross-sectional cohort study of consecutively born singleton term healthy infants born to mothers with various BMIs. Excluded were infants with major factors known to be associated with a potential increase in fetal erythropoiesis. Prepregnancy maternal BMI was calculated from maternal recollection.Result:There was a significant correlation between EPO concentrations and maternal BMI (R=0.427, P=0.007). This correlation remained significant in multiple stepwise regression analysis using the EPO concentration as the dependent variable, and maternal age, parity, gestational age and Apgar scores (1 or 5 min) as potential confounders.Conclusion:Cord blood concentrations of EPO correlate with maternal BMI. We speculate that increasing maternal BMI may represent a relative hypoxic burden on the fetus.

Original languageEnglish
Pages (from-to)29-31
Number of pages3
JournalJournal of Perinatology
Volume35
Issue number1
DOIs
StatePublished - 3 Jan 2015

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