TY - JOUR
T1 - Effect of low energy laser (He-Ne) irradiation on embryo implantation rate in the rat
AU - Stein, A.
AU - Kraicer, P. F.
AU - Oron, U.
PY - 1997
Y1 - 1997
N2 - Attempts to date to increase the rate of embryo implantation, for example by assisting embryo hatching from the zona pellucida, have failed. Recently, several studies have suggested the biostimulating effect of low power laser irradiation. The objective of this study was therefore to examine the potential of low power laser irradiation of the uterus to enhance embryo implantation rate in the rat. Rat blastocysts were flushed from the uterus on day 5 of gestation. They were transferred to the uteri of pseudopregnant recipients on day 4 or 5 of pseudopregnancy. One cornu of the recipient uterus was irradiated (10,30, or 120 sec.); the other was used as control. On day 5 of pregnancy, irradiation did not change implantation rate after 10 or 30 sec of irradiation while 120 sec. of irradiation significantly decreased embryonic implantation. On the other hand, on day 4 of pregnancy, 120 sec. of radiation allowed embryonic implantation to a level similar to that seen after synchronized transfer (39% compared to 42% respectivly). Conclusion: He-Ne Laser irradiation of the exposed rat uterus can attenuate embryo implantation rate.
AB - Attempts to date to increase the rate of embryo implantation, for example by assisting embryo hatching from the zona pellucida, have failed. Recently, several studies have suggested the biostimulating effect of low power laser irradiation. The objective of this study was therefore to examine the potential of low power laser irradiation of the uterus to enhance embryo implantation rate in the rat. Rat blastocysts were flushed from the uterus on day 5 of gestation. They were transferred to the uteri of pseudopregnant recipients on day 4 or 5 of pseudopregnancy. One cornu of the recipient uterus was irradiated (10,30, or 120 sec.); the other was used as control. On day 5 of pregnancy, irradiation did not change implantation rate after 10 or 30 sec of irradiation while 120 sec. of irradiation significantly decreased embryonic implantation. On the other hand, on day 4 of pregnancy, 120 sec. of radiation allowed embryonic implantation to a level similar to that seen after synchronized transfer (39% compared to 42% respectivly). Conclusion: He-Ne Laser irradiation of the exposed rat uterus can attenuate embryo implantation rate.
KW - Blastocyst
KW - He-Ne laser
KW - Implantation
KW - Uterus Rats
UR - http://www.scopus.com/inward/record.url?scp=0031290016&partnerID=8YFLogxK
U2 - 10.1117/12.297986
DO - 10.1117/12.297986
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AN - SCOPUS:0031290016
SN - 0277-786X
VL - 3198
SP - 24
EP - 30
JO - Proceedings of SPIE - The International Society for Optical Engineering
JF - Proceedings of SPIE - The International Society for Optical Engineering
T2 - Effects on Low-Power Light on Biological Systems
Y2 - 8 September 1997 through 8 September 1997
ER -