Effect of low energy laser (He-Ne) irradiation on embryo implantation rate in the rat

A. Stein*, P. F. Kraicer, U. Oron

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

Abstract

Attempts to date to increase the rate of embryo implantation, for example by assisting embryo hatching from the zona pellucida, have failed. Recently, several studies have suggested the biostimulating effect of low power laser irradiation. The objective of this study was therefore to examine the potential of low power laser irradiation of the uterus to enhance embryo implantation rate in the rat. Rat blastocysts were flushed from the uterus on day 5 of gestation. They were transferred to the uteri of pseudopregnant recipients on day 4 or 5 of pseudopregnancy. One cornu of the recipient uterus was irradiated (10,30, or 120 sec.); the other was used as control. On day 5 of pregnancy, irradiation did not change implantation rate after 10 or 30 sec of irradiation while 120 sec. of irradiation significantly decreased embryonic implantation. On the other hand, on day 4 of pregnancy, 120 sec. of radiation allowed embryonic implantation to a level similar to that seen after synchronized transfer (39% compared to 42% respectivly). Conclusion: He-Ne Laser irradiation of the exposed rat uterus can attenuate embryo implantation rate.

Original languageEnglish
Pages (from-to)24-30
Number of pages7
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3198
DOIs
StatePublished - 1997
EventEffects on Low-Power Light on Biological Systems - San Remo, Italy
Duration: 8 Sep 19978 Sep 1997

Keywords

  • Blastocyst
  • He-Ne laser
  • Implantation
  • Uterus Rats

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