Effect of guinea pig or monkey colonic mucus on Shigella aggregation and invasion of HeLa cells by Shigella flexneri 1b and 2a

G. Dinari, T. L. Hale, O. Washington, S. B. Formal

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The effects of guinea pig and rhesus monkey colonic mucus preparations on Shigella aggregation and invasion of HeLa cell monolayers by Shigella flexneri serotype 1b, 2a, and 5 strains were investigated. Guinea pig mucus caused agglutination of S. flexneri serotype 1b but not of S. flexneri serotype 2a or 5. Guinea pig mucus also inhibited HeLa cell invasion by S. flexneri serotypes 1b and 2a. Monkey mucus neither agglutinated any Shigella strain nor inhibited HeLa cell invasion.

Original languageEnglish
Pages (from-to)975-978
Number of pages4
JournalInfection and Immunity
Volume51
Issue number3
DOIs
StatePublished - 1986
Externally publishedYes

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