Abstract
Diluted Dead-Sea brine and solutions of certain of its salts (chlorides and bromides of Na, K and Mg) were found to reversibly inhibit cell proliferation in culture.Bromides were more powerful as inhibitors than their chloride counterparts, and K salts were more effective than those of Na and Mg. KBr had the strongest inhibitory effect, which equalled that of diluted Dead-Sea brine at the same concentration. The favourable results of the Dead-Sea Spa treatment of psoriasis may thus be partly due to the penetration of min erals into the body, via the skin, with subsequent reinforcement of anti-prolifcrativcmechanisms.
| Original language | English |
|---|---|
| Pages (from-to) | 339-347 |
| Number of pages | 9 |
| Journal | Pharmacology |
| Volume | 35 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1987 |
| Externally published | Yes |
Keywords
- Bromides
- Cell culture
- Cell growth
- Cell proliferation
- Dead-sea brain
- Dead-sea salts
- Psoriasis treatment
- Thymidine incorporation