Effect of colchicine on polymorphonuclear leucocyte chemotaxis in human volunteers.

M. Ehrenfeld, M. Levy, M. Bar Eli, R. Gallily, M. Eliakim

Research output: Contribution to journalArticlepeer-review

Abstract

1 The effect of colchicine on polymorphonuclear leucocyte chemotaxis was assessed in eight healthy volunteers. Four of them received 1.0 mg colchicine and the other four received placebo daily for 8 successive days. 2 Chemotaxis decreased significantly within 24 h of the ingestion of colchicine; the values remained low throughout the 8 days of treatment and returned to normal within 48 h of cessation of medication. 3 There were no significant changes in the placebo treated subjects. 1980 The British Pharmacological Society

Original languageEnglish
Pages (from-to)297-300
Number of pages4
JournalBritish Journal of Clinical Pharmacology
Volume10
Issue number3
DOIs
StatePublished - Sep 1980

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