Effect of antiinflammatory drugs on the phagocytic activity of peripheral blood monocytes

B. Klein, A. Tiomny, A. Globerson, I. Elian, I. Notti, M. Djaldetti

Research output: Contribution to journalArticlepeer-review

Abstract

The phagocytic ability of the peripheral blood monocytes was studied before and after ingestion of various nonsteroidal antiinflammtory drugs for five consecutive days by healthy subjects. Administration of the drugs caused a significant decrease in the number of phagocytozed bacteria per cell on days 3 day 5, in comparison with the control group as well as a decreased percentage of total phagocytozing cells. The role of prostaglandins (Pg) in modulating the monocyte function is discussed.

Original languageEnglish
Pages (from-to)321-330
Number of pages10
JournalProstaglandins Leukotrienes and Essential Fatty Acids
Volume9
Issue number3
DOIs
StatePublished - Sep 1982

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