The phagocytic ability of the peripheral blood monocytes was studied before and after ingestion of various nonsteroidal antiinflammtory drugs for five consecutive days by healthy subjects. Administration of the drugs caused a significant decrease in the number of phagocytozed bacteria per cell on days 3 day 5, in comparison with the control group as well as a decreased percentage of total phagocytozing cells. The role of prostaglandins (Pg) in modulating the monocyte function is discussed.
|Number of pages||10|
|Journal||Prostaglandins Leukotrienes and Essential Fatty Acids|
|State||Published - Sep 1982|