Effect of amantadine on sexual dysfunction in neuroleptic-treated male schizophrenic patients

Avi Valevski*, Ilan Modai, Elena Zbarski, Zvi Zemishlany, Abraham Weizman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Twelve male schizophrenic outpatients treated with neuroleptics took part in an open-label drug study to assess the impact of co-administration of amantadine hydrochloride (100 mg daily for 6 weeks) on sexual function Amantadine improved the patients' scores in three out of four areas of sexual function: desire (p<0.02), erection (p<0.05), and satisfaction from sexual performance (p<0.05); there was no change in ejaculatory function. Amantadine may be effective for improving sexual function in male schizophrenic patients receiving neuroleptic medication.

Original languageEnglish
Pages (from-to)355-357
Number of pages3
JournalClinical Neuropharmacology
Volume21
Issue number6
StatePublished - Nov 1998

Keywords

  • Amantadine
  • Neuroleptics
  • Schizophrenia
  • Sexual dysfunction

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