TY - JOUR
T1 - Effect of alcohol on bacterial hemolysis
AU - Shirron, Natali
AU - Korem, Moshe
AU - Shuster, Amir
AU - Leikin-Frenkel, Alicia
AU - Rosenberg, Mel
PY - 2008/10
Y1 - 2008/10
N2 - Hemolysis of blood agar is broadly used as a diagnostic tool for identifying and studying pathogenic microorganisms. We have recently shown that alcohol vapors can confer hemolytic properties on otherwise nonhemolytic fungi (microbial alcohol-conferred hemolysis; MACH). Until now, this phenomenon has been found in various yeast strains and other fungi, but only in a few bacterial species (e.g., staphylococci). In the current study we (1) determined the extent of the above phenomenon in various Gram-positive and Gram-negative laboratory bacterial strains and in clinical bacterial isolates, (2) validated the observed hemolysis using a quantitative technique, and (3) provided evidence that the observed alcohol-mediated hemolysis may, at least in part, be related to synthesis of hemolytic lipids.
AB - Hemolysis of blood agar is broadly used as a diagnostic tool for identifying and studying pathogenic microorganisms. We have recently shown that alcohol vapors can confer hemolytic properties on otherwise nonhemolytic fungi (microbial alcohol-conferred hemolysis; MACH). Until now, this phenomenon has been found in various yeast strains and other fungi, but only in a few bacterial species (e.g., staphylococci). In the current study we (1) determined the extent of the above phenomenon in various Gram-positive and Gram-negative laboratory bacterial strains and in clinical bacterial isolates, (2) validated the observed hemolysis using a quantitative technique, and (3) provided evidence that the observed alcohol-mediated hemolysis may, at least in part, be related to synthesis of hemolytic lipids.
UR - http://www.scopus.com/inward/record.url?scp=50249132438&partnerID=8YFLogxK
U2 - 10.1007/s00284-008-9196-7
DO - 10.1007/s00284-008-9196-7
M3 - מאמר
AN - SCOPUS:50249132438
VL - 57
SP - 318
EP - 325
JO - Current Microbiology
JF - Current Microbiology
SN - 0343-8651
IS - 4
ER -