EFFECT OF A SINGLE DOSE OF DIMETHYL SULPHOXIDE ON RENAL AMYLOIDOSIS

Mordchai Ravid*, Igal Kedar (Keizman), Ezra Sohar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

An amyloid-like fibrillar substance was obtained under certain chemical conditions from the urine of 11 patients with amyloid nephropathy who had been given a test dose of dimethyl sulphoxide. This fibrillar material could not be produced in the urine from 9 patients with proteinuria due to other causes. This finding may be useful in the diagnosis of amyloid nephropathy and could lead to a new approach to therapy.

Original languageEnglish
Pages (from-to)730-731
Number of pages2
JournalThe Lancet
Volume309
Issue number8014
DOIs
StatePublished - 2 Apr 1977
Externally publishedYes

Funding

FundersFunder number
Division of Research Resources
National Institutes of HealthROICa 199397-01, CRR-73
John A. Hartford Foundation

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