TY - JOUR
T1 - EFFECT OF A SINGLE DOSE OF DIMETHYL SULPHOXIDE ON RENAL AMYLOIDOSIS
AU - Ravid, Mordchai
AU - Kedar (Keizman), Igal
AU - Sohar, Ezra
N1 - Funding Information:
Institutes of Health, Bethesda, Maryland for preparing the etiocho-lanolone : Dr. Henry Strade, of Organon Inc., West Orange, N. J. for supplying ’Deca-Durabolin’ (nandrolone); Miss Carol Fisher for the excellent technical assistance; and Mrs Josephine Smeraski for prepar- ing the manuscript. This study was supported by grants from John A. Hartford Founda- tion, Inc., National Institutes of Health grant ROICa 199397-01 and CRR-73 from the General Clinical Research Centers Program of the Division of Research Resources, National Institutes of Health. Requests for reprints should be addressed to E. C. B., Medical Col- lege of Pennsylvania, Department of Medicine, Division of Hemat- ology/Oncology, 3300 Henry Avenue, Philadelphia, Pennsylvania 19129, U.S.A.
PY - 1977/4/2
Y1 - 1977/4/2
N2 - An amyloid-like fibrillar substance was obtained under certain chemical conditions from the urine of 11 patients with amyloid nephropathy who had been given a test dose of dimethyl sulphoxide. This fibrillar material could not be produced in the urine from 9 patients with proteinuria due to other causes. This finding may be useful in the diagnosis of amyloid nephropathy and could lead to a new approach to therapy.
AB - An amyloid-like fibrillar substance was obtained under certain chemical conditions from the urine of 11 patients with amyloid nephropathy who had been given a test dose of dimethyl sulphoxide. This fibrillar material could not be produced in the urine from 9 patients with proteinuria due to other causes. This finding may be useful in the diagnosis of amyloid nephropathy and could lead to a new approach to therapy.
UR - http://www.scopus.com/inward/record.url?scp=0017603051&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(77)92171-7
DO - 10.1016/S0140-6736(77)92171-7
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AN - SCOPUS:0017603051
SN - 0140-6736
VL - 309
SP - 730
EP - 731
JO - The Lancet
JF - The Lancet
IS - 8014
ER -