TY - JOUR
T1 - ECMM CandiReg—A ready to use platform for outbreaks and epidemiological studies
AU - on behalf of the European Confederation of Medical Mycology (ECMM)
AU - Koehler, Philipp
AU - Arendrup, Maiken Cavling
AU - Arikan-Akdagli, Sevtap
AU - Bassetti, Matteo
AU - Bretagne, Stéphane
AU - Klingspor, Lena
AU - Lagrou, Katrien
AU - Meis, Jacques F.
AU - Rautemaa-Richardson, Riina
AU - Schelenz, Silke
AU - Hamprecht, Axel
AU - Koehler, Felix C.
AU - Kurzai, Oliver
AU - Salmanton-García, Jon
AU - Vehreschild, Jörg Janne
AU - Alanio, Alexandre
AU - Alastruey-Izquierdo, Ana
AU - Arsic Arsenijevic, Valentina
AU - Gangneux, Jean Pierre
AU - Gow, Neil A.R.
AU - Hadina, Suzana
AU - Hamal, Petr
AU - Johnson, Elizabeth
AU - Klimko, Nikolay
AU - Lass-Flörl, Cornelia
AU - Mares, Mihai
AU - Özenci, Volkan
AU - Papp, Tamas
AU - Roilides, Emmanuel
AU - Sabino, Raquel
AU - Segal, Esther
AU - Talento, Alida Fe
AU - Tortorano, Anna Maria
AU - Verweij, Paul E.
AU - Hoenigl, Martin
AU - Cornely, Oliver A.
N1 - Publisher Copyright:
© 2019 Blackwell Verlag GmbH
PY - 2019/10/1
Y1 - 2019/10/1
N2 - Background: Recent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance. Objectives: Triggered by the emergence of C auris and by increasing antifungal resistance rates the European Confederation of Medical Mycology developed an international Candida Registry (FungiScope™ CandiReg) to allow contemporary multinational surveillance. Methods: CandiReg serves as platform for international cooperation to enhance research regarding invasive Candida infections. CandiReg uses the General Data Protection Regulation compliant data platform ClinicalSurveys.net that holds the electronic case report forms (eCRF). Data entry is supported via an interactive macro created by the software that can be accessed via any Internet browser. Results: CandiReg provides an eCRF for invasive Candida infections that can be used for a variety of studies from cohort studies on attributable mortality to evaluations of guideline adherence, offering to the investigators of the 28 ECMM member countries the opportunity to document their cases of invasive Candida infection. CandiReg allows the monitoring of epidemiology of invasive Candida infections, including monitoring of multinational outbreaks. Here, we describe the structure and management of the CandiReg platform. Conclusion: CandiReg supports the collection of clinical information and isolates to improve the knowledge on epidemiology and eventually to improve management of invasive Candida infections. CandiReg promotes international collaboration, improving the availability and quality of evidence on invasive Candida infection and contributes to improved patient management.
AB - Background: Recent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance. Objectives: Triggered by the emergence of C auris and by increasing antifungal resistance rates the European Confederation of Medical Mycology developed an international Candida Registry (FungiScope™ CandiReg) to allow contemporary multinational surveillance. Methods: CandiReg serves as platform for international cooperation to enhance research regarding invasive Candida infections. CandiReg uses the General Data Protection Regulation compliant data platform ClinicalSurveys.net that holds the electronic case report forms (eCRF). Data entry is supported via an interactive macro created by the software that can be accessed via any Internet browser. Results: CandiReg provides an eCRF for invasive Candida infections that can be used for a variety of studies from cohort studies on attributable mortality to evaluations of guideline adherence, offering to the investigators of the 28 ECMM member countries the opportunity to document their cases of invasive Candida infection. CandiReg allows the monitoring of epidemiology of invasive Candida infections, including monitoring of multinational outbreaks. Here, we describe the structure and management of the CandiReg platform. Conclusion: CandiReg supports the collection of clinical information and isolates to improve the knowledge on epidemiology and eventually to improve management of invasive Candida infections. CandiReg promotes international collaboration, improving the availability and quality of evidence on invasive Candida infection and contributes to improved patient management.
KW - Candidemia
KW - epidemiology
KW - invasive candidiasis
KW - invasive fungal infection
KW - outbreak
UR - http://www.scopus.com/inward/record.url?scp=85070057545&partnerID=8YFLogxK
U2 - 10.1111/myc.12963
DO - 10.1111/myc.12963
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:85070057545
SN - 0933-7407
VL - 62
SP - 920
EP - 927
JO - Mycoses
JF - Mycoses
IS - 10
ER -