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ECCO consensus on management of inflammatory bowel disease in low- and middle-income countries

  • Alaa El-Hussuna*
  • , Almuthe Christina Hauer
  • , Tarkan Karakan
  • , Valerie Pittet
  • , Henit Yanai
  • , Jalpa Devi
  • , Jesus K. Yamamoto-Furusho
  • , Ali Reza Sima
  • , Hailemichael Desalegn
  • , Mutaz Idrees Sultan
  • , Vishal Sharma
  • , Hany Shehab
  • , Lamya Mrabti
  • , Natalia Queiroz
  • , Anuraag Jena
  • , Andy Darma
  • , Karin Davidson
  • , Nicolas Avellaneda
  • , Muhammed Elhadi
  • , April Roslani
  • Dakshitha Wickramasinghe, Carlo Angelo Cajucom, Shaji Sebastian
*Corresponding author for this work
  • Odda-Helse Fonna
  • OpenSourceResearch Organization (OSRC.Network)
  • Medical University of Graz
  • Gazi University
  • University Center for Primary Care and Public Health
  • Rabin Medical Center Israel
  • Washington University St. Louis
  • Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
  • Masoud Gastroenterology and Hepatology Center
  • St. Paul‘s Hospital Millennium Medical College
  • Al-Quds University
  • Postgraduate Institute of Medical Education and Research
  • Cairo University
  • Hospital Mohammed VI
  • Gastroenterologia
  • Siksha ‘O’ Anusandhan University
  • Soetomo General Hospital (FK UNAIR)
  • Cape Town
  • Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno
  • University of Tripoli
  • Korea University
  • University of Malaya
  • University of Colombo
  • Metro Manila and Philippine Society of Colon and Rectal Surgeons (PSCRS)
  • Hull University Teaching Hospitals NHS Trust
  • Hull York Medical School

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

Background The incidence and prevalence of inflammatory bowel disease [IBD] have increased significantly in low- and middle-income countries [LMICs] in recent decades. Managing IBD in these settings presents substantial challenges. This consensus aims to describe the epidemiology of IBD in LMICs and to highlight the key challenges in its diagnosis and treatment. Method The consensus-defining strategy followed the previous European Crohn's and Colitis Organisation [ECCO] consensus guidelines [available at www.ecco-ibd.eu]. The authors reviewed the available evidence and formulated statements accordingly. Provisional ECCO statements and supporting text were drafted based on a comprehensive literature review and further refined through two voting rounds, which included external reviewers and national representatives from ECCO's 36 member countries. The final ECCO statements, representing a consensus of at least 80% agreement among participants, were approved during an online meeting. Consensus statements should be interpreted in context with their accompanying commentary rather than in isolation and should not be used solely to guide patient management. The supporting text was finalized under the guidance of each working group leader [VP, HY, TK, AH] and subsequently integrated by the consensus leader [AE]. Results Data on IBD epidemiology in LMICs remain limited. Public and healthcare professional awareness and timely access to early diagnostic modalities, advanced medical and surgical therapies, and specialist multidisciplinary care are key gaps in IBD care in LMICs. The complexity and chronic nature of IBD, along with the necessity for a multidisciplinary approach, pose significant challenges to adopting a holistic management strategy in LMICs. Conclusion There is a critical need for further studies to assess the specific needs of LMICs. Such research will help guide resource allocation and improve IBD management in these settings.

Original languageEnglish
Article numberjjaf125
JournalJournal of Crohn's and Colitis
Volume20
Issue number1
DOIs
StatePublished - 1 Jan 2026

Funding

Funders
Viviana Parra Izquierdo
Vishwa Mohan Dayal
Iago Rodr guez-Lago
Safwat Odeh and Adeyeye Ademola
Aya Hammami, Tunisia
Syed Shariq Hasan
European Crohn's and Colitis Organisation

    Keywords

    • Crohn's disease
    • IBD
    • LMICs
    • diagnosis
    • inflammatory bowel disease
    • low- and middle-income settings
    • treatment
    • ulcerative colitis

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