Early detection of essential hypertension by time-frequency analysis

L. R. Davrath; Y. Goren; I. Pinhas; D. David; S. Akselrod

Early detection of essential hypertension by time-frequency analysis

L. R. Davrath^*, Y. Goren, I. Pinhas, D. David, S. Akselrod

^*Corresponding author for this work

Clinical Departments

Tel Aviv University

Research output: Contribution to journal › Conference article › peer-review

1 Scopus citations

Abstract

Hypertension affects approximately 25% of adults in industrialized countries and contributes significantly to morbidity and mortality from cardiovascular diseases. Young adult, normotensive offspring of one hypertensive parent (KHT, n=12) and normotensive offspring of two normotensive parents (YN, n=14) participated. ECG, continuous blood pressure, and respiration were recorded. Time-frequency decomposition of these signals was performed by a Continuous Wavelet Transform. During change in posture (CP), KHT demonstrated a significantly greater increase in the low frequency fluctuations in heart rate (HR) than YN, indicating enhanced sympathetic involvement in the HR response to CP. Upon recovery from Handgrip, vagal reactivation was more sluggish in KHT. These results indicate possible malfunctions in both branches of autonomiccontrol in individuals at increased risk of hypertension.

Original language	English
Pages (from-to)	445-448
Number of pages	4
Journal	Computers in Cardiology
Volume	29
State	Published - 2002
Event	Computers in Cardiology 2002 - Memphis, TN, United States Duration: 22 Sep 2002 → 25 Sep 2002

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AU - Goren, Y.

AU - Pinhas, I.

AU - David, D.

AU - Akselrod, S.

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N2 - Hypertension affects approximately 25% of adults in industrialized countries and contributes significantly to morbidity and mortality from cardiovascular diseases. Young adult, normotensive offspring of one hypertensive parent (KHT, n=12) and normotensive offspring of two normotensive parents (YN, n=14) participated. ECG, continuous blood pressure, and respiration were recorded. Time-frequency decomposition of these signals was performed by a Continuous Wavelet Transform. During change in posture (CP), KHT demonstrated a significantly greater increase in the low frequency fluctuations in heart rate (HR) than YN, indicating enhanced sympathetic involvement in the HR response to CP. Upon recovery from Handgrip, vagal reactivation was more sluggish in KHT. These results indicate possible malfunctions in both branches of autonomiccontrol in individuals at increased risk of hypertension.

AB - Hypertension affects approximately 25% of adults in industrialized countries and contributes significantly to morbidity and mortality from cardiovascular diseases. Young adult, normotensive offspring of one hypertensive parent (KHT, n=12) and normotensive offspring of two normotensive parents (YN, n=14) participated. ECG, continuous blood pressure, and respiration were recorded. Time-frequency decomposition of these signals was performed by a Continuous Wavelet Transform. During change in posture (CP), KHT demonstrated a significantly greater increase in the low frequency fluctuations in heart rate (HR) than YN, indicating enhanced sympathetic involvement in the HR response to CP. Upon recovery from Handgrip, vagal reactivation was more sluggish in KHT. These results indicate possible malfunctions in both branches of autonomiccontrol in individuals at increased risk of hypertension.

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Y2 - 22 September 2002 through 25 September 2002

ER -

Early detection of essential hypertension by time-frequency analysis

Abstract

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