Drugging multiple same-allele driver mutations in cancer

Ruth Nussinov*, Mingzhen Zhang, Ryan Maloney, Hyunbum Jang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations
Original languageEnglish
Pages (from-to)823-828
Number of pages6
JournalExpert Opinion on Drug Discovery
Volume16
Issue number8
DOIs
StatePublished - 2021

Funding

FundersFunder number
U.S. Government
National Institutes of HealthHHSN26120080001E
U.S. Department of Health and Human Services
National Cancer InstituteZIABC010441

    Keywords

    • Drug resistance
    • activating mutations
    • cancer
    • double mutations
    • drug discovery
    • k-ras
    • pi3k
    • signaling

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