Drug allergy in hospitalized perioperative patients: the contribution of a structured questionnaire for accurate diagnosis

Polina Klieman, Brian Fredman, Arnon Goldberg, Ronit Confino-Cohen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Aims: History of drug allergy is a major cause for deviation from standard of care, as well as prescribing expensive medications. We aimed to evaluate drug allergy-related history taking by surgery interns and compare it with history taking by an allergist and an anesthetist using a simple, structured questionnaire. Methods: Patients with a declared drug allergy were prospectively recruited from surgical wards. The interns' drug allergy diagnosis was compared with that of the allergy specialist and anesthetist that used a structured questionnaire. Results: A total of 195 patients with 305 reports of drug allergy were included; 52% of the reactions labeled by the surgical interns as allergic were tagged as not allergic by the anesthetist assisted by the questionnaire. The allergist found that 51% of these reactions represented either side effects or were nonrelated to the culprit drug. Conclusion: Inconsistency between drug allergy diagnosis of surgery interns and anesthetists and allergists are common. The use of a simple structured questionnaire by the ward physicians may be accessible and beneficial for more precise diagnosis of drug allergies.

Original languageEnglish
Pages (from-to)837-841
Number of pages5
JournalImmunotherapy
Volume5
Issue number8
DOIs
StatePublished - Aug 2013

Keywords

  • allergist consultation
  • drug allergy
  • drug allergy questionnaire
  • drug-related adverse effects
  • perioperative drug allergy

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