@article{b83f139c98554918b7db8979390097e5,
title = "DRD4 exon III polymorphism and response to risperidone in Israeli adolescents with schizophrenia: A pilot pharmacogenetic study",
abstract = "This study examined the possible association between the polymorphism in the dopamine receptor DRD4 gene and response to risperidone among 24 Israeli Jewish adolescent inpatients with first-episode schizophrenia. Response was categorically determined by a change of >40\% on the Brief Psychiatric Rating Scale (BPRS). No significant association was found between the DRD4 genotype and clinical response, although carriers of <7 repeat alleles demonstrated higher response rate (10/20 vs. 0/4, P=0.11). Studies in larger groups of adolescent schizophrenia patients are warranted to clarify the possible association between DRD4 exon III repeat alleles and the response to risperidone.",
keywords = "Adolescence, Dopamine, Pharmacogenetics, Polymorphism, Risperidone",
author = "Gil Zalsman and Amos Frisch and Shaul Lev-Ran and Andr{\'e}s Martin and Elena Michaelovsky and Daniela Bensason and Doron Gothelf and Eitan Nahshoni and Samuel Tyano and Abraham Weizman",
note = "Funding Information: This work was supported by the The National Institute for Psychobiology in Israel—The Charles Smith Foundation. Grant No. 9b-99.",
year = "2003",
month = may,
doi = "10.1016/S0924-977X(03)00006-3",
language = "אנגלית",
volume = "13",
pages = "183--185",
journal = "European Neuropsychopharmacology",
issn = "0924-977X",
publisher = "Elsevier B.V.",
number = "3",
}