Down’s Syndrome and Alzheimer’s Disease: Are Common Genes From Human Chromosome 21 Involved In Both Disorders?

Y. Groner; N. Dafni; L. Sherman; D. Levanon; Y. Bernstein; E. Danciger; O. Elroy-Stein; A. Neer

doi:10.1007/978-1-4613-2179-8_34

Down’s Syndrome and Alzheimer’s Disease: Are Common Genes From Human Chromosome 21 Involved In Both Disorders?

Y. Groner, N. Dafni, L. Sherman, D. Levanon, Y. Bernstein, E. Danciger, O. Elroy-Stein, A. Neer

Weizmann Institute of Science

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Why do most victims of Down’s syndrome (D.S.) develop Alzheimer’s dementia (A.D.) in middle age? The intriguing links between D.S, an inborn chromosomal disorder, and A.D, a condition that develops late in life in individuals with no obvious genetic abnormality were recognized many years ago. Nevertheless, the actual metabolic faults underlying both these conditions are still unknown (1–3).

Original language	American English
Title of host publication	Alzheimer’s and Parkinson’s Disease: Strategies for Research and Development
Editors	Abraham Fisher, Israel Hanin, Chaim Lachman
Place of Publication	Boston, MA
Publisher	Springer US
Pages	271-283
Number of pages	13
ISBN (Print)	978-1-4613-2179-8
DOIs	https://doi.org/10.1007/978-1-4613-2179-8_34
State	Published - 1986
Externally published	Yes

Publication series

Name	Advances in Behavioral Biology
Publisher	Springer
Volume	29

Access to Document

10.1007/978-1-4613-2179-8_34

Cite this

Groner, Y., Dafni, N., Sherman, L., Levanon, D., Bernstein, Y., Danciger, E., Elroy-Stein, O., & Neer, A. (1986). Down’s Syndrome and Alzheimer’s Disease: Are Common Genes From Human Chromosome 21 Involved In Both Disorders? In A. Fisher, I. Hanin, & C. Lachman (Eds.), Alzheimer’s and Parkinson’s Disease: Strategies for Research and Development (pp. 271-283). ( Advances in Behavioral Biology; Vol. 29). Springer US. https://doi.org/10.1007/978-1-4613-2179-8_34

Groner, Y. ; Dafni, N. ; Sherman, L. et al. / Down’s Syndrome and Alzheimer’s Disease: Are Common Genes From Human Chromosome 21 Involved In Both Disorders?. Alzheimer’s and Parkinson’s Disease: Strategies for Research and Development. editor / Abraham Fisher ; Israel Hanin ; Chaim Lachman. Boston, MA : Springer US, 1986. pp. 271-283 ( Advances in Behavioral Biology).

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title = "Down{\textquoteright}s Syndrome and Alzheimer{\textquoteright}s Disease: Are Common Genes From Human Chromosome 21 Involved In Both Disorders?",

abstract = "Why do most victims of Down{\textquoteright}s syndrome (D.S.) develop Alzheimer{\textquoteright}s dementia (A.D.) in middle age? The intriguing links between D.S, an inborn chromosomal disorder, and A.D, a condition that develops late in life in individuals with no obvious genetic abnormality were recognized many years ago. Nevertheless, the actual metabolic faults underlying both these conditions are still unknown (1–3).",

author = "Y. Groner and N. Dafni and L. Sherman and D. Levanon and Y. Bernstein and E. Danciger and O. Elroy-Stein and A. Neer",

year = "1986",

doi = "10.1007/978-1-4613-2179-8_34",

language = "American English",

isbn = "978-1-4613-2179-8",

series = " Advances in Behavioral Biology",

publisher = "Springer US",

pages = "271--283",

editor = "Abraham Fisher and Israel Hanin and Chaim Lachman",

booktitle = "Alzheimer{\textquoteright}s and Parkinson{\textquoteright}s Disease: Strategies for Research and Development",

address = "United States",

}

Groner, Y, Dafni, N, Sherman, L, Levanon, D, Bernstein, Y, Danciger, E, Elroy-Stein, O & Neer, A 1986, Down’s Syndrome and Alzheimer’s Disease: Are Common Genes From Human Chromosome 21 Involved In Both Disorders? in A Fisher, I Hanin & C Lachman (eds), Alzheimer’s and Parkinson’s Disease: Strategies for Research and Development. Advances in Behavioral Biology, vol. 29, Springer US, Boston, MA, pp. 271-283. https://doi.org/10.1007/978-1-4613-2179-8_34

Down’s Syndrome and Alzheimer’s Disease: Are Common Genes From Human Chromosome 21 Involved In Both Disorders? / Groner, Y.; Dafni, N.; Sherman, L. et al.
Alzheimer’s and Parkinson’s Disease: Strategies for Research and Development. ed. / Abraham Fisher; Israel Hanin; Chaim Lachman. Boston, MA: Springer US, 1986. p. 271-283 ( Advances in Behavioral Biology; Vol. 29).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review