Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1

Keyphrases

• Dopamine 100%
• Overexpression 100%
• Autosomal Recessive 100%
• Neurodegeneration 100%
• Parkin 100%
• Viral Vectors 100%
• Juvenile Parkinsonism 100%
• Globus Pallidus 33%
• Substantia Nigra 33%
• Striatal 33%
• Ubiquitination 33%
• Pharmacological Inhibitors 33%
• Gene Transfer 33%
• Cell Inhibition 33%
• Rapid Onset 33%
• Neurotoxicity 33%
• PC12 Cells 33%
• Ubiquitin Ligase 33%
• Neuron-specific 33%
• Tyrosine Hydroxylase 33%
• Nigral Dopaminergic Neuron 33%
• Dopamine Synthesis 33%
• Striatal Dopamine Level 33%
• Recombinant Adeno-associated Virus (rAAV) 33%
• Septin 33%
• Parkin mutation 33%
• Parkin Gene 33%
• Dopamine Secretion 33%

Neuroscience

• Neurodegeneration 100%
• Parkin 100%
• Virus Vector 100%
• Parkinsonism 60%
• Globus pallidus 20%
• Dopaminergic Neuron 20%
• Substantia nigra 20%
• Dopamine Release 20%
• Adeno-Associated Virus 20%
• Gene Delivery 20%
• Neurotoxicity 20%
• Gene Transfer 20%
• Tyrosine Hydroxylase 20%
• Ubiquitination 20%
• Ubiquitin Protein Ligase 20%
• Septin 20%