Dopamine D4 receptor gene polymorphism and personality traits in healthy volunteers

M. L. Persson*, D. Wassermann, T. Geijer, A. Frisch, R. Rockah, E. Michaelovsky, A. Apter, A. Weizmann, E. G. Jönsson, H. Bergmann

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


An association between long alleles of a variable number tandem repeat (VNTR) polymorphism in the dopamine receptor D4 gene and the extraversion related personality traits Excitement and Novelty Seeking has been reported in healthy subjects. In an attempt to replicate the previous findings, 256 healthy Caucasian volunteers were analysed for a potential relationship between the dopamine receptor D4 exon III VNTR polymorphism and Extraversion as assessed by the Revised Neo Personality Inventory (NEO PI-R). The present study did not yield evidence for an association between Extraversion and the dopamine receptor D4 polymorphism.

Original languageEnglish
Pages (from-to)203-206
Number of pages4
JournalEuropean Archives of Psychiatry and Clinical Neuroscience
Issue number4
StatePublished - 2000


  • Dopamine receptor D4
  • Excitement-Seeking
  • Genetics
  • Personality inventory
  • Polymorphism


Dive into the research topics of 'Dopamine D4 receptor gene polymorphism and personality traits in healthy volunteers'. Together they form a unique fingerprint.

Cite this